Differential association of two PTPN22 coding variants with Crohn’s disease and ulcerative colitis

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Ulcerative colitis and Crohns disease: molecular genetics and clinical implications.

Derek Jewell Professor of Gastroenterology, Gastroenterology Unit, Radcliffe Infirmary, Oxford, OX2 6HE, UK. Tel: +44 (0) 1865 224829; Fax: +44 (0) 1865 790792; E-mail: [email protected] The genetics of inflammatory bowel disease (IBD) is an area of enormous topical interest. Crohn’s disease is one of the first polygenic diseases in which a susceptibility gene (NOD2 ) ...

متن کامل

Ulcerative oesophagitis in association with ulcerative colitis.

Ulcerative colitis is primarily a disease of the large bowel, but a wide variety of extracolonic complications of the disease are now recognized (Edwards and Truelove, 1964), and a number of these occur in other parts of the alimentary tract. In the mouth, aphthous ulcers and monilial infections arise as a result of the general debility caused by the colitis (Grieve, 1964). Gastritis and small ...

متن کامل

Crohn's disease from ulcerative colitis. Ulcerative colitis and Crohn's disease

were studied, using an indirect immunoperoxidase technique. These findings were compared with the immunoglobulin containing cell number in colonic biopsies from 10 control patients with no evidence of colitis. In biopsies from the 20 patients with inflammatory bowel disease a marked increase in area of the lamina propria per millimetre mucosa length was found. In ulcerative colitis a marked inc...

متن کامل

association of oral manifestations with ulcerative colitis

aim : the study aims to document the oral lesions in patients with uc. background : inflammatory bowel disease (ibd) is comprised of two chronic, tissue-destructive and clinical entities including crohn's disease (cd) and ulcerative colitis (uc), both of which are immunologically based. patients and methods : the population of the study includes fifty patients with uc, as the experimental group...

متن کامل

The Study of Upper Gastrointestinal Endoscopy in Patients with Inflammatory Bowel Disease and Ulcerative Colitis

Background and aims: In diagnosing inflammatory bowel disease, one of diagnostic way is upper gastrointestinal endoscopy, which helps in differential diagnosis of unspecified colitis as well. The aim of this study was to investigate the necessity of upper gastrointestinal endoscopy in patients with inflammatory bowel disease.   Materials and Methods: In this descriptive cross-sectional...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Journal of Translational Medicine

سال: 2010

ISSN: 1479-5876

DOI: 10.1186/1479-5876-8-s1-p2